This drug was first marketed in the U.
It appears that it was marketed after a limited number of controlled clinical trials a total of only patients and a series of uncontrolled studies. Some of the studies reported anxiolytic, muscle relaxant, hypnotic, and amnesic actions.
2400 Cautions Special procedures are required for diabetics taking neurontin and extreme care if used for patients with renal insufficiency. Dose As an anticonvulsant — neurontin. Maximum value of 3, mgs. Same dose as for anticonvulsant use U.
Its mechanism of action is unknown, but it appears to increase GABA turnover in several regions of the brain. Absorption and Fate Neurontin is not metabolized by the body, 2400 mg of neurontin, i.
It is eliminated solely by renal excretion, 2400 mg of neurontin. For elderly patients and those with renal insufficiency, the elimination neurontin is up 2400 52 hours. For others it is quoted as 5 — 7 hours.
Dependency Potential and Withdrawal Symptoms All references warn of avoiding abrupt withdrawal and the use of a tapered withdrawal. Some references suggest the 2400 potential is low, but this generally refers to short-term use and that it can significantly increase with long-term use.
Neurontin symptoms reported include — anxiety, insomnia, nausea, 2400 mg of neurontin, pain, sweating, vomiting, severe and repeated seizures, ataxia, nystagmus, fatigue and dizziness.
An epileptic patient should not stop taking Neurontin, 2400 mg of neurontin, or he may increase his risk of having a seizure. Depression Neurontin may have effects on the brain. Specifically, Neurontin may cause a patient to feel depressed, according to MayoClinic.
This occurs because Neurontin increase the levels of GABA, which may slow down nerve conduction in the part of the brain that is related to mood, 2400 mg of neurontin. Thus, a patient taking Neurontin may begin to feel depressed after beginning treatment. He may 2400 have interest in activities that he used to neurontin interested in, and he may have difficulty completing work or other daily task.
In more severe cases of depression, a patient may have thoughts of suicide. Thus, a patient should not hesitate to let his doctor know that he is beginning to feel depressed.
Rapid Eye Movement Drugs. This effect occurs because Neurontin affects nerves that control the eyes, which can cause rapid eye movement.
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