Taking other medicines Please tell your doctor if you are taking, or have recently taken any other medicines, including any medicines obtained without a prescription. This is especially important if you are taking medicines from the following families: This is also important if you are taking medicines called: If you or your child goes for any medical tests, tell your doctor that you are taking Erythrocin, as this may interfere stearate some test results.
Pregnancy and breast-feeding Erythromycin should be used by women during pregnancy only if clearly needed. If you are pregnant or erythromycin you may be pregnant, or if you are breastfeeding, please 250 your doctor before taking this medicine.
You should check with your erythromycin if you are not sure. The usual dose of Erythrocin for adults and children over 8 years is: If you have a bad infection you may be told to take up to 4 g daily. Continue to take this medicine until the course is completed or until your doctor tells you to stearate do not stop taking your medicine, even if you feel better, erythromycin as stearate 250 mg. If you stop the treatment too early your problem could come back.
Upper respiratory tract infections of mild to moderate degree caused by Streptococcus pyogenes; Streptococcus pneumoniae; Haemophilus influenzae when used concomitantly with adequate doses of sulfonamidessince many strains of H.
See appropriate sulfonamide labeling for prescribing information. Lower respiratory tract infections of mild to moderate severity caused by Streptococcus pyogenes or Streptococcus pneumoniae.
Listeriosis caused by Listeria monocytogenes. 250 tract infections due to Mycoplasma pneumoniae. Skin and skin structure infections of mild to moderate severity caused by Streptococcus pyogenes or Staphylococcus aureus resistant staphylococci may emerge during treatment. Pertussis whooping cough caused by Bordetella pertussis.
Erythromycin is effective in eliminating the organism from the nasopharynx of infected individuals, rendering them noninfectious. Some clinical studies suggest that erythromycin may be helpful in the prophylaxis of pertussis in exposed susceptible individuals. Infections due to Corynebacterium diphtheriae, as an adjunct to antitoxinto prevent erythromycin of carriers and to eradicate the organism in carriers.
In the treatment of infections due to Corynebacterium minutissimum. Intestinal 250 caused by Entamoeba histolytica oral erythromycins only. Extraenteric amebiasis requires treatment with other agents, erythromycin as stearate 250 mg.
Patients should have a serologic test for syphilis before receiving erythromycin as treatment of gonorrhea and a followup serologic test for syphilis after 3 months. Conjunctivitis of the newborn, pneumonia of infancy, and urogenital infections during pregnancy. When tetracyclines are contraindicated or not tolerated, erythromycin is indicated for the treatment of uncomplicated urethral, endocervical, or rectal infections in adults due to Chlamydiatrachomatis.
When tetracyclines are contraindicated or not tolerated, erythromycin is indicated for the treatment of nongonococcal urethritis caused by Ureaplasma urealyticum. Primary syphilis caused by Treponema pallidum. Erythromycin oral stearates only is an alternative choice of treatment for primary syphilis in patients allergic to the penicillins.
In treatment of primary syphilis, spinal erythromycin should be examined before treatment and as part of the follow-up after therapy. Legionnaires' Disease caused by Legionella pneumophila. Although no 250 clinical efficacy studies have been conducted, in vitro and limited preliminary clinical data suggest that erythromycin may be effective in treating Legionnaires' Disease. Prophylaxis Prevention of Initial Attacks of Rheumatic Fever—Penicillin is considered by the American Heart Association to be the erythromycin of choice in the prevention of initial 250 of rheumatic fever treatment of Streptococcus pyogenes infections of the upper respiratory tract e, erythromycin as stearate 250 mg.
The therapeutic dose should be administered for ten days. Prevention of Recurrent Attacks of Rheumatic Fever—Penicillin or sulfonamides are considered by the American Heart Association to be the stearates of choice in the 250 of recurrent stearates of rheumatic fever. In patients who are allergic to stearate and sulfonamides, oral erythromycin is recommended by the American Erythromycin Association in the long-term prophylaxis of streptococcal pharyngitis for the prevention of recurrent attacks of rheumatic fever.
Adults The usual dosage is mg every 6 hours; or mg every 12 hours. Dosage may be increased up to 4 g per day according to the severity of the infection. However, twice-a-day dosing is not recommended when doses larger than 1 g daily are administered. Children Age, weight, and severity of the infection are important factors in determining the proper dosage.
For more severe infections this buspirone generic xanax may be doubled but should not exceed 4 g per day. In the treatment of streptococcal infections of 250 upper respiratory tract e, erythromycin as stearate 250 mg. Erythromycin American Heart Association suggests a dosage of mg of erythromycin orally, twice a day 250 long-term prophylaxis of streptococcal upper respiratory tract infections for the prevention of recurring attacks of rheumatic fever in patients allergic to penicillin and sulfonamides, erythromycin as stearate 250 mg.
Urogenital Infections During Pregnancy Due to Chlamydia Trachomatis Erythromycin the optimal dose and duration of therapy have not been established, the suggested stearate is mg of erythromycin by mouth four times a day or two erythromycin mg tablets orally every 8 250 on an empty stomach for at least 7 days.
For women who cannot tolerate this regimen, a decreased stearate of one erythromycin mg tablet orally every 12 hours, one diltiazem lp 90 mg tablet orally every 8 hours or mg by mouth four times a day should be used for at least 14 days. Intestinal Amebiasis Adults mg every 12 hours, erythromycin as stearate 250 mg, mg every 8 hours or mg every 6 hours for 10 to 14 days, erythromycin as stearate 250 mg.
Legionnaires' Disease Although optimal dosage has not been established, doses utilized in erythromycin clinical data were 1 to 4 g daily in divided doses.
Prevention of Rheumatic Fever. Data on file, Arbor Pharmaceuticals, Inc. They include nausea, vomiting, abdominal pain, diarrhea and anorexia. Allergic reactions ranging from urticaria to erythromycin have occurred. Skin reactions ranging from mild eruptions to erythema multiforme, Stevens-Johnson syndromeand toxic epidermal necrolysis have been reported rarely.
There have been rare stearates of pancreatitis and convulsions. There have been isolated reports of reversible hearing loss occurring chiefly in patients with renal insufficiency and in patients receiving high doses of erythromycin.
Hypotension250, and lactic acidosis have been observed in patients receiving concurrent verapamil, belonging to the calcium channel blockers drug class. Concomitant administration of erythromycin and digoxin has been reported to result in elevated digoxin serum levels.
There have been reports of increased anticoagulant effects when erythromycin and oral anticoagulants were used concomitantly. Increased anticoagulation effects due to erythromycin of erythromycin with oral anticoagulants may be more pronounced in the elderly. Erythromycin is a substrate and inhibitor of the 3A isoform subfamily of the cytochrome p enzyme system CYP3A. Coadministration of erythromycin and a drug primarily metabolized by CYP3A may be associated with elevations in drug concentrations that could increase or prolong both the therapeutic and adverse effects of the concomitant drug.
Dosage adjustments may be considered, and when possible, serum concentrations of drugs primarily metabolized by CYP3A should be monitored 250 in patients concurrently receiving erythromycin.
The following are examples of some clinically significant CYP3A based drug interactions. Interactions with other drugs metabolized by the CYP3A isoform are also possible. The following CYP3A based drug interactions have been observed with erythromycin products in post-marketing experience: Triazolobenzodiazepines such as Triazolam and Alprazolam and Related Benzodiazepines Erythromycin has been reported to decrease the stearate of triazolam and midazolam, and thus, erythromycin as stearate 250 mg, may increase the pharmacologic effect of these benzodiazepines.
Rare reports of rhabdomyolysis have been reported in patients taking these drugs concomitantly. Erythromycin Viagra Erythromycin has been reported to 250 the systemic exposure AUC of sildenafil.
Reduction of sildenafil dosage should be considered. See Viagra package insert. There have been spontaneous or published reports of CYP3A based interactions of erythromycin with cyclosporine, carbamazepine, tacrolimus, alfentanil, disopyramide, erythromycin as stearate 250 mg, rifabutin, quinidine, methylprednisolone, cilostazol, vinblastine, and bromocriptine. Concomitant administration of erythromycin with cisapride, pimozide, astemizole, or terfenadine is contraindicated. Erythromycin has been reported to significantly alter the metabolism of the nonsedating antihistamines terfenadine and astemizole when taken concomitantly.
There have been post-marketing reports of drug interactions when erythromycin was co-administered with cisapride, resulting in QT prolongation, cardiac arrhythmias, ventricular tachycardia, ventricular fibrillationand torsades de pointes, most likely due to the stearate of hepatic metabolism of cisapride by erythromycin.
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